Tal Danino: Programiranje bakterija kako bi se borile protiv raka

Programiranje bakterija kako bi se borile protiv raka

Celu lekciju pogledajte na: https://ed.ted.com/lessons/hacking-bacteria-to-fight-cancer-tal-danino

Godine 1884. pacijent koji je imao galopirajući rak u vratu je dobio nepovezanu kožnu bakterijsku infekciju. Kako se oporavio od infekcije rak je iznenada krenuo da se smanjuje. Infekcija je stimulisala pacijentov imuni sistem. Danas, sintetički biolozi programiraju bakterije da bezbedno dostave lekove direktno tumorima. Kako je ovo moguće? Tal Danino istražuje.

Lekciju smislio Tal Danino, režirao Kris Bišop.

Cancer cells can sometimes be outsmarted by one of humanity’s oldest adversaries: bacteria. Over a century after a patient’s bacterial infection triggered his cancer’s disappearance, scientists now program bacteria to deliver medicine directly inside tumors. By tweaking bacterial DNA and building biological circuits, these living agents seek out cancer, release drugs, and even activate the immune system for a stronger attack. Synthetic biology opens the door to disease-fighting bacteria that sense, treat, and prevent illness from within the body.