Timp de zeci de ani, cercetătoarea Mina Bissell a urmărit o idee revoluţionară -- aceea că o celulă canceroasă nu devine automat o tumoră, ci, mai degrabă, depinde de celulele care o înconjoară (micromediul său) pentru indicii legate de dezvoltarea sa. Mina Bissell ne împărtăşeşte cele două experimente-cheie care au dovedit că teoria dominantă despre dezvoltarea cancerului e eronată.

Mina Bissell: Experimente sugerând o nouă perspectivă asupra cancerului

A cancer cell’s behavior is shaped by the tissue architecture and context surrounding it, not only by mutations in its DNA. In a striking experiment, cells with cancer genes formed part of a healthy feather in a chicken embryo, but became tumors only when removed from their environment. With 70 trillion cells in one human body, the microenvironment’s influence can mean the difference between health and disease. Understanding how cells respond to their surroundings opens new ways to prevent and treat cancer.

Cancer’s Fate Depends on Its Neighborhood, Not Just Its Genes

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TED Stage Talk

Mina Bissell: Mina Bissell: Experimente sugerând o nouă perspectivă asupra cancerului