Andrea M. Henle: How CRISPR lets you edit DNA

How CRISPR lets you edit DNA

From the smallest single-celled organism to the largest creatures on Earth, every living thing is defined by its genes. With recent advancements, scientists can change an organism's fundamental features in record time using gene editing tools such as CRISPR. But where did this medical marvel come from and how does it work? Andrea M. Henle examines the science behind this new technology. [Directed by Adam Wells, narrated by Susan Zimmerman, music by Chris Reed].

Gene editing has become dramatically faster and more precise thanks to CRISPR, a tool adapted from a natural bacterial defense system. Scientists now use CRISPR to change DNA in plants, animals, and humans, unlocking possibilities from drought-proof crops to potential cures for genetic diseases. By guiding molecular scissors to any gene, nearly any trait can be altered as easily as correcting a typo. However, ethical dilemmas and unpredictable effects accompany this newfound power to rewrite life.